CRL-Rodent Genetics and Genetic Quality Control for Inbred and F1 Hybrid Strains, Part 1
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چکیده
This document reviews the development of such animals by selection and inbreeding, defines basic genetic terms and concepts, and describes how breeders prevent and detect genetic contamination. It ends with an introduction to genetic quality control, including a brief discussion of colony management. Genetic monitoring, the main component of quality control, is detailed in the 1992 document, Part II of this series. The subject of transgenics is covered in other issues.
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